NaturaLift MD Review Blog

Coenzyme Q-10 (Ubiquinone)

Fifteen German doctors and scientists stated in a recently published study about coenzyme Q-10:

“We have investigated whether topical application CoQ-10 has the beneficial effect of preventing photoaging. We are able to demonstrate that CoQ-10 penetrated into the viable layers of the epidermis and reduced the level of oxidation measured by weak photon emission. Furthermore, a reduction in wrinkle depth following CoQ-10 application was also shown. CoQ-10 was determined to be effective against UV-A mediated oxidative stress in human keratinocytes(Cells in the primary outer layer of our epidermis.) in terms of thiol depletion, activation of specific phosphotyrosine kinases(A class of enzymes.) and prevention of oxidative DNA damage. CoQ-10 was also able to significantly suppress the expression of collagenase(The harmful enzyme that dissolves the skin’s collagen.) in human dermal fibroblasts following UV-A irradiation. These results indicate that CoQ-10 has the efficacy to prevent many of the detrimental effects
of photoaging.”

Here’s how ten skin specialists described the results of their skin studies using coenzyme Q-10:

“We demonstrated a diminished resistance in keratinocytes of old donors against UV irradiation. This reduced epidermal resistance against oxidative stressors, i.e.: UV irradiation, can be improved by topical application of CoQ-10.”

They also stated:

“Our in vivo investigations shows that wrinkles around the region of the eyes could be reduced by long-term application of CoQ-10.”

Dosage is critical for best results. Doctors performed experiments to evaluate the penetration of coenzyme Q-10 in the skin. They stated: “… [c]oenzyme Q-10 skin levels were found to be directly related to the concentration employed and the contact time.” In another study which evaluated topical application and skin levels CoQ-10, researchers observed: “… high concentrations of CoQ-10 may be achieved in the skin by topical treatment.”

In another experiment, researchers used only a 0.05% concentration of topical coenzyme Q-10, and achieved: “… a significant increase that peaked after 60 days.” However, this increase was only in the sebum(The fatty substance secreted on top of the skin). There was no significant concentration in the stratum corneum(The outermost epidermis layer).

Therefore, concentration is very important. That’s why we based ours on science: to give you the most effective concentration available. As the pervious authors stated: “Coenzyme Q-10 levels were found to be directly related to the concentrations employed and the contact time…” That’s why we use a high concentration and recommend application at least twice a day to maximize the affect of our optimally formulated Therapy.